Quick Answer: How Long Does It Take For Paget’S Disease To Progress?

What is the most common age for females to be diagnosed with Paget’s disease?

Paget’s disease of the breast occurs most often in women older than age 50.

Most women with Paget’s disease of the breast have underlying ductal breast cancer, either in situ — meaning in its original place — or, less commonly, invasive breast cancer..

How do you treat Paget’s disease of the breast?

Treatment of Paget’s disease of the breast will generally begin with surgery. Once the surgery has been performed, additional treatments may also be used, including: Surgery. Surgery to remove the affected tissue may include breast-sparing techniques or the removal of the entire breast.

How can you tell the difference between Paget’s disease and eczema?

Paget’s disease can look like other skin conditions such as eczema or psoriasis. But there are differences. For example, Paget’s disease affects the nipple from the start while eczema generally affects the areola and only rarely affects the nipple.

Is Paget’s disease fatal?

Others have symptoms and complications. Pain is the most common symptom. Depending on which of your bones are affected by Paget’s disease, you might have other symptoms and complications, such as those listed below. Although rare, the most serious complication of Paget’s disease is bone cancer.

Is Paget’s disease curable?

There’s currently no cure for Paget’s disease of bone, but treatment can help relieve the symptoms.

What are the stages of Paget disease?

Three phases of Paget disease have been described: lytic, mixed lytic and blastic, and sclerotic. In an individual patient, different skeletal lesions may progress at different rates. Thus, at any one time, multiple stages of the disease may be demonstrated in different skeletal regions.

What does Paget’s disease feel like?

Symptoms of Paget’s disease of the nipple It appears as a red, scaly rash on the skin of the nipple and areola. The affected skin is often sore and inflamed, and it can be itchy or cause a burning sensation. The nipple can sometimes be ulcerated.

Is Pagets disease serious?

Paget’s disease of bone can sometimes lead to further, potentially serious problems. These include: fragile bones that break more easily than normal. enlarged or misshapen bones.

What bones are often affected by Paget’s disease?

Paget’s disease of bone interferes with your body’s normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, the disease can cause affected bones to become fragile and misshapen. Paget’s disease of bone most commonly occurs in the pelvis, skull, spine and legs.

What is the survival rate for Paget disease?

For women with both Paget disease of the breast and invasive cancer in the same breast, the 5-year relative survival declined with increasing stage of the cancer (stage I, 95.8 percent; stage II, 77.7 percent; stage III, 46.3 percent; stage IV, 14.3 percent) (1, 3, 8, 9).

How is Paget’s disease diagnosed and treated?

During the physical exam, your doctor will examine areas of your body that are causing you pain. He or she may also order X-rays and blood tests that can help confirm the diagnosis of Paget’s disease of bone.

What virus causes Paget’s disease?

Paget’s disease may be caused by a slow virus infection (i.e., paramyxoviridae) present for many years before symptoms appear. Associated viral infections include respiratory syncytial virus, canine distemper virus, and the measles virus.

Does Paget’s disease respond to steroid cream?

Prognosis generally good if treatment initiated early. Differential diagnoses. This condition is often confused with dermatitis, but pruritus associated with the latter usually resolves with topical steroid treatment, whereas in Paget’s disease of the nipple it does not.

Can symptoms of Paget’s disease come and go?

Paget’s disease causes the skin on and around the nipple to become red, sore, and flaky, or scaly. At first, these symptoms tend to come and go. Over time, symptoms of Paget’s disease usually worsen and may include: itching, tingling, and/or a burning sensation.

How aggressive is Paget’s disease of the breast?

As a noninvasive form of cancer, Paget’s is not considered an aggressive or fast-moving disease, but it is often associated with another cancer in the same breast.